KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
166 [KT] 2024년도 봄학기 AI 석사과정 (카이스트, 포항공대, 한양대 진학) 신입생 모집(~8/15) file 생명과학과 2023.08.01 408
165 [LG마그나] 2024년 상반기 신입사원 채용 및 산학장학생 모집 (~3/31) file 생명과학과 2024.03.05 6
164 [LG전자] 2024년 상반기 신입사원 채용 (~3.24까지) file 생명과학과 2024.03.05 2
163 [LG화학] 2024년 3월 신입사원 모집 (~3.25까지) file 생명과학과 2024.03.05 9
162 [LIG넥스원] 2021년 상반기 LIG넥스원 신입/경력 공개채용 생명과학과 2021.03.02 987
161 [LIG넥스원] 2021년 상반기 채용상담/설명회 일정 안내 생명과학과 2021.02.26 1002
160 [LIG넥스원] 2023 상반기 LIG넥스원 수시채용 생명과학과 2023.03.07 135
159 [LIG넥스원] 2024년 상반기 LIG넥스원 공개채용(~3/17) file 생명과학과 2024.03.05 13
158 [LIG넥스원]2021 상반기 신입/경력사원 공개채용(~3/14) 생명과학과 2021.02.23 339
157 [LINE] 2021 SW개발 신입 LINER 공개채용 생명과학과 2021.03.02 275
156 [LS전선] 2021 상반기 LS전선 채용연계형 인턴 모집 (~4/7 (수), 23시59분) 생명과학과 2021.04.01 226
155 [LX인터내셔널] 2024년 상반기 신입사원 채용(채용연계형 인턴십) (~3.24까지) file 생명과학과 2024.03.05 3
154 [NAVER] 2021 네이버 신입 공채 : 기술 직군 (~4.12) 생명과학과 2021.04.02 203
153 [NAVER] 2023 팀네이버 신입 공채 (~4.10 월 오전 11시) 생명과학과 2023.03.31 145
152 [NAVER] 2024 팀네이버 신입 공채(~3/18 11시까지) file 생명과학과 2024.03.05 4
151 [NC문화재단] 프로젝토리 크루 모집 (~4.23) 생명과학과 2021.04.06 194
150 [NIH] KVSTA Fellowship 2023 공고 file 생명과학과 2023.05.04 191
149 [PMI] 2022년 하반기 한국필립모리스 INKOMPASS 채용전환형 인턴십 모집 (8/22~9/4) 생명과학과 2022.08.30 184
» [Post Doc] Dr, Jian Xu at Children's Research Institute, UT Southwestern Medical Center file 생명과학과 2022.05.23 262
147 [Post-doc] Columbia university Irving Medical Center 채용 생명과학과 2021.12.08 364
Board Pagination Prev 1 2 3 4 5 6 7 8 9 10 ... 12 Next
/ 12