KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
110 휴온스 21년 상반기 신입 영업직군 수시채용 (~2.28 접수마감) 생명과학과 2021.02.22 198
109 한국투자증권] CEO LIVE 채용설명회 안내 (참가시 서류전형 우대) 생명과학과 2021.04.20 102
108 한국산업은행 2021년 하반기 신입행원(5급) 채용 (~3.26(금) 16시까지) 생명과학과 2021.03.16 147
107 지아이이노베이션 모집공고_수시채용 file 생명과학과 2021.07.13 266
106 제7회 BIO 창업 아이디어 경진대회_5/17~24일 file 생명과학과 2021.05.04 146
105 연세대학교 IBS 나노의학연구단 박사후 연구원/석사후 연구원 모집(9/9~채용시 마감) 생명과학과 2021.09.16 330
104 안전한 개인정보보호 사례 공모전(9/1~10.8) file 생명과학과 2021.08.26 180
103 미래과학기술지주(주) 신입/경력 채용 공고 file 생명과학과 2022.06.24 10
102 네이버 광고상품 기획, 광고플랫폼 기획 인턴십 모집(~2/28까지) 생명과학과 2021.02.18 272
101 기초과학연구원(IBS) 인지 및 사회성 연구단 file 생명과학과 2020.11.30 1234
100 ㈜테라자인 사원 (연구원) 채용 공고_2021.09.28- 2021.10.28 생명과학과 2021.09.30 315
99 ㈜지투지바이오_채용공고 생명과학과 2020.12.24 615
98 ◼︎두산그룹 2021 상반기 채용연계형 인턴 모집 (~3/15) 생명과학과 2021.03.02 174
97 ■ 신한라이프 공채 1기 신입사원 채용 (~4/11) 생명과학과 2021.04.01 124
96 [현대카드/현대캐피탈/현대커머셜] 2021 Summer Internship 인재모집 (~4/7, 14시) 생명과학과 2021.04.01 126
95 [현대모비스] 각 부문/BU별 대규모 신입사원 채용 (~ 3월 둘째 주) 생명과학과 2021.02.25 220
94 [한화파워시스템] 2021년 상반기 경력사원 채용(~5/17) 생명과학과 2021.05.04 123
93 [한화파워시스템] 2021년 상반기 경력사원 채용 생명과학과 2021.04.19 95
92 [한화디펜스] 한화디펜스 대졸신입사원 채용(채용전제형 인턴) 생명과학과 2021.04.21 113
91 [한온시스템] 2021년 채용연계형 인턴 모집 (~3/22) 생명과학과 2021.03.10 165
Board Pagination Prev 1 2 3 4 5 6 Next
/ 6