KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
118 [롯데케미칼] 카이스트 2022 런치설명회 진행 file 생명과학과 2022.09.07 266
117 [삼성바이오로직스] '22년(하) 신입사원 모집 file 생명과학과 2022.09.07 371
116 [삼성바이오로직스] '22년 하반기 온라인 채용설명회 file 생명과학과 2022.09.02 316
115 [KAIST 자연과학연구소] 연구교원 채용 file 생명과학과 2022.09.02 320
114 [ASML Korea] 2022년 하반기 ASML Korea 신입사원 채용(8/29~9/20) file 생명과학과 2022.09.01 167
113 [PMI] 2022년 하반기 한국필립모리스 INKOMPASS 채용전환형 인턴십 모집 (8/22~9/4) 생명과학과 2022.08.30 183
112 [Postdoctoral fellow posiotion] UT Southwestern Medical Center file 생명과학과 2022.07.28 312
111 [Postdoctoral Fellow Positions] University Children’s Hospital Zürich file 생명과학과 2022.07.25 317
110 미래과학기술지주(주) 신입/경력 채용 공고 file 생명과학과 2022.06.24 315
109 (주)씨앤큐어 2022년 상반기 연구원 채용 공고 file 생명과학과 2022.06.22 272
108 [일리미스테라퓨틱스(주)] R&D그룹 연구원 석사/박사 채용 생명과학과 2022.06.08 399
» [Post Doc] Dr, Jian Xu at Children's Research Institute, UT Southwestern Medical Center file 생명과학과 2022.05.23 260
106 [추가 선발] 물리학과 박용근 교수님 연구실 (BioMedical Optics Laboratory) 학부 연구원 모집 안내 (마감연장: 05/08) file 생명과학과 2022.04.04 508
105 [Post-doc] Columbia university Irving Medical Center, Department of Psychiatry 채용 생명과학과 2022.03.02 437
104 [이화여자대학교] 2022학년도 2학기 이화여자대학교 전임교원 초빙 공고 생명과학과 2022.02.22 611
103 [Post-doc] Duke-NUS Medical School 채용 생명과학과 2022.02.08 405
102 [DB문화재단] DB 장학생 봉사단 8기 모집 생명과학과 2021.12.09 326
101 [전문연구요원] (주)토모큐브 2022 전문연구요원 채용공고_Science Team file 생명과학과 2021.12.09 309
100 [Post-doc] Columbia university Irving Medical Center 채용 생명과학과 2021.12.08 363
99 [셀트리온] 분야별 신입/경력 수시채용 file 생명과학과 2021.10.20 713
Board Pagination Prev 1 2 3 4 5 6 7 8 9 Next
/ 9