KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
224 [추가 선발] 물리학과 박용근 교수님 연구실 (BioMedical Optics Laboratory) 학부 연구원 모집 안내 (마감연장: 05/08) file 생명과학과 2022.04.04 715
223 [채용설명회] ’23년 기술보증기금 캠퍼스 리크루팅 안내 file 생명과학과 2023.05.02 314
222 [채용] 애스톤사이언스㈜ 연구원 모집 공고 생명과학과 2020.10.08 1870
221 [차병원·바이오그룹] 신입/Junior 대규모 공채 (~10/17(목) 24시까지) file 생명과학과 2024.10.08 59
220 [차병원·바이오그룹] R&D분야 임원/박사급 공채(기간 연장 ~6/9) file 생명과학과 2024.05.30 204
219 [차그룹] 2020 하반기 경력 및 신입공채 (~10/18) file 생명과학과 2020.09.28 1386
218 [존슨앤드존슨] [2024 여름 인턴십 채용 (~5/19) file 생명과학과 2024.05.03 306
217 [존슨앤드존슨] J&J MedTech 인턴십 채용 (~11/12) file 생명과학과 2024.10.31 40
216 [전문연구요원] (주)토모큐브 2022 전문연구요원 채용공고_Science Team file 생명과학과 2021.12.09 500
215 [잡코리아] '2021 혁신성장 청년인재 집중양성' 홍보 생명과학과 2021.03.11 360
214 [일본 현지취업] 일본 채용면접회 JOBHAKU KOREA 안내 : AGC(아사히글라스), 히타치하이시스템21, 도쿄가스엔지니어링 등 총 14개사 채용 진행 file 생명과학과 2024.08.09 85
213 [일리미스테라퓨틱스(주)] R&D그룹 연구원 석사/박사 채용 생명과학과 2022.06.08 554
212 [인테그리스코리아] 2024 Summer Internship 모집 (~5/26) file 생명과학과 2024.05.20 118
211 [이화여자대학교] 2022학년도 2학기 이화여자대학교 전임교원 초빙 공고 생명과학과 2022.02.22 849
210 [이수그룹] 이수그룹 신입 공개채용 (~4/15(월) 오전 10시까지) file 생명과학과 2024.03.26 122
209 [이수그룹] 2023 하반기 이수그룹 신입사원 모집 (~10/18(수)10:00) file 생명과학과 2023.09.26 249
208 [원진바이오테크놀로지] ADC 개발자 채용공고 (~.07.11) file 생명과학과 2023.06.12 306
207 [여천NCC] 2024 하반기 여천NCC 대졸사원 채용(신입/경력) (~10/21(월) 15시까지) file 생명과학과 2024.10.08 32
206 [아모레퍼시픽] 2021 상반기 AMOREPACIFIC 신입사원 수시채용(~5/21) 생명과학과 2021.05.10 594
205 [아모레퍼시픽] 2021 상반기 AMOREPACIFIC 신입사원 수시채용(~5/19) 생명과학과 2021.05.04 461
Board Pagination Prev 1 2 3 4 5 6 7 8 9 10 ... 17 Next
/ 17