KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
334 [선진] 2022년 하반기 선진 신입, 경력 공개채용(~10/3) file 생명과학과 2022.09.19 885
333 2021 상반기 BGF리테일 신입&전역(예정)장교 채용 생명과학과 2021.03.29 883
332 ■ 신한라이프 공채 1기 신입사원 채용 (~4/11) 생명과학과 2021.04.01 879
331 (주)한샘 키친&바스영업전문직(KD) 대규모 공개채용 (21년 3월) (~3/17까지 접수) 생명과학과 2021.03.08 872
330 2021 상반기 SBS 신입사원 공개채용 (~3/2 화) 생명과학과 2021.02.18 871
329 2021 LG화학 R&D 신입사원 모집(석박사) 생명과학과 2021.04.13 867
328 [LINE] 2021 SW개발 신입 LINER 공개채용 생명과학과 2021.03.02 867
327 ['21년 상반기 삼성바이오로직스 온라인 채용설명회 안내] 생명과학과 2021.03.10 866
326 [서울문화재단] 2021년 제1차 서울문화재단 직원 공개채용(~03/22) 생명과학과 2021.03.05 860
325 [동원그룹] 2021 상반기 채용연계형 인턴모집 (~5/13) 생명과학과 2021.05.10 851
324 [PMI] 2022년 하반기 한국필립모리스 INKOMPASS 채용전환형 인턴십 모집 (8/22~9/4) 생명과학과 2022.08.30 849
323 휴온스 21년 상반기 신입 영업직군 수시채용 (~2.28 접수마감) 생명과학과 2021.02.22 844
322 2021년 야생동물 실태조사 전문인력 양성교육 모집 file 생명과학과 2021.05.04 841
321 한국투자증권] CEO LIVE 채용설명회 안내 (참가시 서류전형 우대) 생명과학과 2021.04.20 841
320 [스마일게이트] 2021년 스마일게이트 직무체험 인턴십 모집 (5/11~5/25) 생명과학과 2021.05.11 840
319 2021 NCSOFT SUMMER INTERN(~5/6 14시) 생명과학과 2021.04.22 828
318 [잡코리아] '2021 혁신성장 청년인재 집중양성' 홍보 생명과학과 2021.03.11 820
317 [싸이티바코리아] 2021 대한민국 바이오의약품 대상 공모전 (7/22~9/26) file 생명과학과 2021.07.27 819
316 [컴투스] 2023 컴투스 SUMMER 인턴십 (GENIUS 5기)( ~ 5/30) file 생명과학과 2023.05.19 811
315 [롯데그룹] 21년 상반기 상시채용 <ZOOM TALK> 안내 생명과학과 2021.04.05 811
Board Pagination Prev 1 2 3 4 5 6 7 8 9 10 ... 21 Next
/ 21