KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
135 [삼성에스원] 2023 상반기 3급 신입사원 채용 (~3/15 17시까지) 생명과학과 2023.03.09 268
134 [LIG넥스원] 2023 상반기 LIG넥스원 수시채용 생명과학과 2023.03.07 263
133 [커리어톡] 대기업 현직 및 인사팀과 함께하는 메타버스 잡페어 (~3/9, 이벤트 중) 생명과학과 2023.03.07 220
132 Open Research Positions - Laboratory of Cancer Ecology and Genomics (University of Michigan) file 생명과학과 2023.03.07 265
131 - [현대카드/현대커머셜] 2023 Internship - 생명과학과 2023.03.06 279
130 삼성바이오로직스 '23년 상반기 온라인 채용설명회 file 생명과학과 2023.03.06 465
129 [WorldQuant] 2023 IQC 대회 (International Quant Championship) 안내 생명과학과 2023.03.03 297
128 2023년 상반기 RIST 공개 채용 file 생명과학과 2023.03.03 301
127 [한화시스템] 2023 방산부문 신입사원 채용 (~3/1) 생명과학과 2023.02.20 287
126 [뷰웍스] 2023 뷰웍스 바이오영상 직무 채용공고 (2/13~2/28) file 생명과학과 2023.02.07 294
125 한국애보트진단 OPDP 모집공고 file 생명과학과 2023.01.27 512
124 [모집 마감] 물리학과 박용근 교수님 연구실 (BioMedical Optics Laboratory) 학부 연구원 모집 안내 (마감: 11/18) Recruiting undergraduate research students - Biomedical Optics Lab (PI: Prof. YongKeun Park, Physics Department) 생명과학과 2022.11.15 490
123 기초과학연구원(IBS) 뇌과학이미징연구단 문준영 교수 연구실에서 연구원을 모집합니다. file 생명과학과 2022.10.06 703
122 [선진] 2022년 하반기 선진 신입, 경력 공개채용(~10/3) file 생명과학과 2022.09.19 456
121 [Post-doc] Mckay Orthopaedic Research Laboratory at University of Pennsylvania file 생명과학과 2022.09.15 328
120 [Post-Doc] the Laboratory of Biomolecular Design in the Departments of Bioengineering and Neurobiology at Stanford University file 생명과학과 2022.09.15 379
119 [갤럭스㈜] 신약설계연구원 모집 file 생명과학과 2022.09.15 333
118 [롯데케미칼] 카이스트 2022 런치설명회 진행 file 생명과학과 2022.09.07 445
117 [삼성바이오로직스] '22년(하) 신입사원 모집 file 생명과학과 2022.09.07 501
116 [삼성바이오로직스] '22년 하반기 온라인 채용설명회 file 생명과학과 2022.09.02 465
Board Pagination Prev 1 ... 5 6 7 8 9 10 11 12 13 14 ... 16 Next
/ 16