KAIST 생명과학과동창회
  • News & Events
  • Recruiting

Recruiting

Postdoc Positions in Cancer Genomics, Epigenetics, Metabolism, and Bioinformatics

 

Multiple postdoctoral positions are available in the lab of Dr. Jian Xu at Children’s Research Institute (CRI), UT Southwestern Medical Center to study the gene regulatory processes that control stem cell development and cancers. We employ genomics, epigenetics, genome editing, metabolomics, and mouse genetics to define disease-associated epigenetic and genetic programs that control normal stem cell development, and how these processes go awry in cancer progression.

 

Our laboratory is equipped with cutting-edge genomics, molecular biology and bioinformatics platforms, and has access to many shared facilities including an in-house illumina sequencer, 10xGenomics singlecell technologies, metabolomics, transgenic mouse core, imaging, and flow cytometry. Our team brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting. Since we established the laboratory in 2014, our team has published a series of impactful papers, which include:

 

 Development of a CRISPR-based CAPTURE approach for in situ analysis of chromatin interactions (Cell 170:1028, 2017)

 Post-transcriptional regulation of mitochondrial biogenesis and metabolism during erythropoiesis (Nature Cell Biology 19:626, 2017)

 Reported that loss of EZH2 reprograms branched-chain amino acid (BCAA) metabolism to drive leukemic transformation (Cancer Discovery 9:1228, 2019)

 Reported an integrative pipeline to identify pathogenic non-coding variants connecting enhancer dysregulation with nuclear receptor signaling in blood cancers (Cancer Discovery 10:724, 2020)

 Discovered that the epigenetic silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia (Nature Genetics 53:672, 2021) 

 

Some potential research projects:

 

 The crosstalk between epigenetic gene regulation and metabolism in development and cancer

 Engineering of CRISPR-based epigenomic editing and chromatin CAPTURE technologies for programmable gene regulation

 Enhancer function and mechanisms in stem cells and cancers

 The function and regulation of genomic transposable elements in development and cancer

 Single-cell lineage tracing of stem cell differentiation and cancer evolution

 

Candidates must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, cancer biology, mouse genetics, bioinformatics and/or a related field. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics, genomics, metabolism, computational biology, mouse genetics, and/or hematologyoncology is strongly preferred.

 

Interested individuals should send a CV, a short summary of research interest and experience, and a list of three references to:

 

Jian Xu, Ph.D.

Associate Professor

Children’s Research Institute

CPRIT Scholar in Cancer Research

UT Southwestern Medical Center

Email: Jian.Xu@UTSouthwestern.edu 


List of Articles
번호 제목 글쓴이 날짜 조회 수
169 [펄어비스] 2023년 게임실무 부트캠프 참가자 모집(~8/13(일)) file 생명과학과 2023.07.28 154
168 [펄어비스] 2023 펄어비스 QA Beginner 인턴 모집( ~ 5/30) file 생명과학과 2023.05.15 155
167 [기아] 2023년 하반기 기아 신입 채용(~9/25(월)17:00) file 생명과학과 2023.09.13 156
166 ★D-4★ [한화정밀기계] 2023 상반기 채용전제형 인턴 채용 (~05/21) 생명과학과 2023.05.17 161
165 [LIG넥스원] 2023 상반기 LIG넥스원 수시채용 생명과학과 2023.03.07 162
164 [고려아연] 2023 하반기 고려아연 및 계열사 신입사원 공개채용 (~10/22(일) 23:59) file 생명과학과 2023.10.11 162
163 [존슨앤드존슨] [2024 여름 인턴십 채용 (~5/19) file 생명과학과 2024.05.03 165
162 [파마리서치] 직무특화 채용연계형 인턴십 모집 (~12/10(일)까지) file 생명과학과 2023.11.21 168
161 - [현대카드/현대커머셜] 2023 Internship - 생명과학과 2023.03.06 171
160 [KT] 2023년 KT 신입사원 채용( ~4/24) file 생명과학과 2023.04.18 177
159 [NAVER] 2023 팀네이버 신입 공채 (~4.10 월 오전 11시) 생명과학과 2023.03.31 177
158 [포스코청암재단] 제15기(2024년) 포스코사이언스펠로십 선발 공고( ~6/30) file 생명과학과 2023.04.17 180
157 [삼양그룹] (D-11) 2023 8월 삼양그룹 대규모 신입사원 수시채용 모집 (~9/18 9시) file 생명과학과 2023.09.07 180
156 [한국타이어] R&D 직무 채용(~5/21) file 생명과학과 2023.05.09 183
155 2023년 한화파워시스템 창원사업장 채용연계형 인턴 채용(~6/5) 생명과학과 2023.05.18 183
154 [현대케피코] 2023 하반기 현대케피코 신입사원 모집(채용연계형 인턴) (~5/21) file 생명과학과 2023.05.10 184
153 2023년 상반기 RIST 공개 채용 file 생명과학과 2023.03.03 185
152 [Post-doc] Columbia University 박사후 연구원 채용 공고 file 생명과학과 2023.12.06 185
151 [삼양그룹] 2023년 7월 삼양그룹 신입사원 채용(~7/31(월)) file 생명과학과 2023.07.18 187
150 [펄어비스] 2023 펄어비스 채용연계형 여름 인턴십 모집 (04.24(월)~05.14(일)) file 생명과학과 2023.04.24 189
Board Pagination Prev 1 2 3 4 5 6 7 8 9 10 ... 14 Next
/ 14